“Buffy the Vampire Slayer ”Actor Nicholas Brendon's Cause of Death Revealed
“Buffy the Vampire Slayer ”Actor Nicholas Brendon's Cause of Death Revealed
Angel Saunders, Rachel McRadyTue, May 5, 2026 at 12:14 PM UTC
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Nicholas Brendon attends Wizard World Comic Con Philadelphia 2017Credit: Gilbert Carrasquillo/Getty -
Nicholas Brendon's cause of death has been revealed
The actor, who was 54 at the time of his death, died from atherosclerotic and hypertensive cardiovascutar disease
The Buffy the Vampire Slayer alum's death was announced on March 20
A cause of death for Nicholas Brendon has been disclosed by the Putnam County Coroner's office.
On May 5, coroner Todd Zeiner announced in a report obtained by PEOPLE that Brendon's death was natural and he died of atherosclerotic and hypertensive cardiovascutar disease. The report lists acute pneumonia and previous myocardial infarction as contributing factors. The "mechanism of death" was 90% blockage right coronary artery.
In the report, Zeiner said law enforcement present at the scene "found no obvious signs of foul play and assisted me with cataloging the scene. Nothing seemed out of place or disturbed."
Zeiner said a longtime friend of Brendon's, Theresa Fortier, was at his residence and called 911. "Theresa stated the decedent had been having a persistent cough and had been self medicating with over the counter medications. He had been complaining about chest pain. She recommended a hospital, but he declined," Zeiner wrote. "He was a longtime smoker and was apprehensive about going due to his recent back surgery. She advised he had a recent heart attack several years ago, but he declined any further treatment at that time."
Nicholas Brendon as Xander Harris in Buffy The Vampire Slayer Year 5Credit: Online USA/Getty
After finding no further evidence at the scene, his body was transported to the coroner for an autopsy, which determined the actor had a "markedly enlarged heart, severe stenosis of the right coronary artery, moderate stenosis of the left anterior descending and left circumflex arteries, acute pneumonia and inflammation of the small bowel. The small bowel inflammation is most likely secondary to ischemic changes related to the cardiogenic shock."
According to the American Heart Association, atherosclerotic cardiovascular disease is a buildup of plaque in the artery walls and is one of the leading causes of death globally.
In videos Brendon filmed from his home's back deck prior to his death, the coroner noted that he was "markedly coughing" and had a "raspy voice." The clips "provided a basis for his declining health," Zeiner said.
The Buffy the Vampire Slayer alum's death was announced in a statement shared on his official Instagram page on Friday, March 20. He was 54 years old.
"We are heartbroken to share the passing of our brother and son, Nicholas Brendon. He passed in his sleep of natural causes," his family said.
His family added that while many knew him for the roles “he brought to life over the years,” Brendon had more recently discovered “his passion in painting and art.”
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Nicholas Brendon attends the 2012 Chicago Comic and Entertainment ExpoCredit: Barry Brecheisen/WireImage
The statement continued, "Those who truly knew him understood that his art was one of the purest reflections of who he was. While it's no secret that Nicholas had struggles in the past, he was on medications and treatment to manage his diagnosis and he was optimistic about the future at the time of his passing. Our family asks for privacy during this time as we grieve his loss and celebrate the life of a man who lived with intensity, imagination and heart. Thank you to everyone who has shown love and support."
Years before his death, Brendon was hospitalized after a "cardiac incident" in August 2022.
At the time, the news was also shared to his Instagram account in a since-deleted post apologizing for the actor not “going live as much lately.”
"Nicky is doing fine now but he had to be rushed to emergency about two weeks ago because of a cardiac incident (tachycardia/arrhythmia). Some of you might remember he had a similar incident after his second spinal surgery last year (for Cauda Equina) but this time,” the post continued.
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One year prior, in August 2021, a rep for the actor said Brendon experienced "deep-seated medical problems and immense pain" around the time he was charged with felony prescription fraud.
Brendon rose to fame playing Xander Harris on Buffy the Vampire Slayer alongside costars Sarah Michelle Gellar, Alyson Hannigan, Charisma Carpenter and David Boreanaz.
The television series aired from 1997 to 2003. He also appeared in movies like Unholy and Coherence.
In the months leading up to his death, the Kitchen Confidential actor was involved in ongoing legal disputes, such as a December 2025 lawsuit for over $120,000, alleging unfinished work on renovations on his home.
On March 12, just eight days before he died, Brendon was accused in a court hearing of mistreating workers and putting an AirTag on a contractor, PEOPLE previously reported.
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Source: “AOL Entertainment”
